患者様へ｜医療関係者様へ

自治医科大学地域医療学センター総合診療部門

研究

2025年業績

?（１）英文論文

  1. Miyagami T, Nishizaki Y, Shimizu T,?Yamamoto Y, Shikino K, Kataoka K, Nojima M, Deshpande G, Naito T, Tokuda Y. Optimal outpatient training for resident physicians’ general medicine in-training examination score: a cross-sectional study. BMC Med Educ. 2025 Jan 11;25(1):49. doi:10.1186/s12909-025-06670-5. PMID: 39799318.
  2. Fujikawa H, Tamune H, Nishizaki Y, Shimizu T, Yamamoto Y, Shikino K, Sekine M, Kobayashi H, Tokuda Y. Association of clinical knowledge with patient care ownership among resident physicians: a nationwide cross-sectional study in Japan. BMC Med Educ. 2025 Jan 16;25(1):77. doi: 10.1186/s12909-025-06694-x. PMID: 39825343.
  3. Hirayama K, Kanda N, Hashimoto H, Yoshimoto H, Goda K, Mitsutake N, Hatakeyama S. Antibiotic Prescription Trends in Dentistry: A Descriptive Study Using Japan’s National Database. J Public Health Dent. 2025 Jan 23. doi: 10.1111/jphd.12663. Epub ahead of print. PMID: 39846316.
  4. Takano H, Kanda N, Wakimoto Y, Ohbe H, Nakamura K. Intravenous immunoglobulin for mortality and inflammatory status in patients with sepsis: a retrospective database study. Front Immunol. 2025 Jan 16;15:1511481. doi: 10.3389/fimmu.2024.1511481. PMID: 39885983; PMCID: PMC11779611.
  5. Hatakeyama J, Nakamura K, Inoue S, Liu K, Yamakawa K, Nishida T, Ohshimo S, Hashimoto S, Kanda N, Aso S, Suganuma S, Maruyama S, Ogata Y, Takasu A, Kawakami D, Shimizu H, Hayakawa K, Yoshida T, Oshima T, Fuchigami T, Yawata H, Oe K, Kawauchi A, Yamagata H, Harada M, Sato Y, Nakamura T, Sugiki K, Hakozaki T, Beppu S, Anraku M, Kato N, Iwashita T, Kamijo H, Kitagawa Y, Nagashima M, Nishimaki H, Tokuda K, Nishida O. Two-year trajectory of functional recovery and quality of life in post-intensive care syndrome: a multicenter prospective observational study on mechanically ventilated patients with coronavirus disease-19. J Intensive Care. 2025 Feb 6;13(1):7. doi: 10.1186/s40560-025-00777-z. PMID: 39915821; PMCID: PMC11800417.
  6. Hemmi M, Kanda N, Nakamura K, Suganuma S, Kawabata K, Kato H, Ichihara N, Asami T, Ide K, Muto Y, Hori M, Iba A, Hosozawa M, Iso H. The relationship between the phenotype of long COVID symptoms and one-year psychosocial outcomes: an exploratory clustering analysis. Psychol Health Med. 2025 Feb 17:1-17. doi: 10.1080/13548506.2025.2465654. Epub ahead of print. PMID: 39961083.
  7. Fujikawa H, Tamune H, Nishizaki Y, Shikino K, Shimizu T, Yamamoto Y, Tokuda Y. Undergraduate general medicine education in Japan: A nationwide cross-sectional survey of medical trainees’ perspectives. J Gen Fam Med. 2024 Nov 10;26(2):148-156. doi: 10.1002/jgf2.752. eCollection 2025 Mar. PMID: 40061388.?
  8. Fujikawa H, Tamune H, Nishizaki Y, Nagasaki K, Kobayashi H, Nojima M, Sekine M, Shimizu T, Yamamoto Y, Shikino K, Tokuda Y. Association between residents’ work hours and patient care ownership: a nationwide cross-sectional study in Japan. BMC Med Educ. 2025 Mar 15;25(1):385. doi: 10.1186/s12909-025-06941-1. PMID: 40089705.?
  9. Masuda H, Yamamoto Y, Ae R. Recurrent Hematochezia Due to a Rectal Fistula Caused by a Left Internal Iliac Artery Aneurysm. Cureus. 2025 Feb 22;17(2):e79483. doi: 10.7759/cureus.79483. PMID: 40135012; PMCID: PMC11933728.
  10. Inaba T, Minami K, Ishioka H, Sekiguchi K, Watanabe A, Hatakeyama S. Isolated brain abscess caused by Aspergillus tubingensis in a patient with alcoholic liver cirrhosis. J Infect Chemother. 2025 May;31(5):102691. doi: 10.1016/j.jiac.2025.102691. Epub 2025 Mar 29. PMID: 40164348.
  11. Hashimoto H, Kanda N, Yoshimoto H, Goda K, Mitsutake N, Hatakeyama S. Significant reduction in antibiotic prescription rates in Japan following implementation of the national action plan on antimicrobial resistance (2016-20): a 9-year interrupted time-series analysis. JAC Antimicrob Resist.
    2025 Apr 30;7(3):dlaf062. doi: 10.1093/jacamr/dlaf062. PMID: 40309498; PMCID: PMC12041918.
  12. Miyagami T, Nishizaki Y, Shimizu T, Yamamoto Y, Shikino K, Kataoka K, Nojima M, Deshpande GA, Naito T, Tokuda Y. Evaluating the Use of a Note-Taking App by Japanese Resident Physicians: Nationwide Cross-Sectional Study. JMIR Form Res. 2025 May 9;9:e55087. doi: 10.2196/55087. PMID: 40344204.
  13. Nagasaki K, Nishizaki Y, Shimizu T, Yamamoto Y, Shikino K, Kataoka K, Kobayashi H, Tokuda Y. Educational environment changes toward resident duty hour restrictions in Japan. Sci Rep. 2025 May 15;15(1):16925. doi: 10.1038/s41598-025-00347-1. PMID: 40374653; PMCID: PMC12081845.
  14. Fujikawa H, Tamune H, Nishizaki Y, Shikino K, Shimizu T, Yamamoto Y, Kobayashi H, Tokuda Y. Hospital Type and Medical Residents’ Patient Care Ownership: A Nationwide Cross-Sectional Study in Japan. Clin Teach. 2025 Aug;22(4):e70109. doi: 10.1111/tct.70109. PMID: 40492715.
  15. Yamamoto Y, Hatakeyama S, Matsumura M, Koike S. Impact of the new Japanesemedical specialty system on residents’ career choices in general medicine: anationwide cross-sectional study. BMC Med Educ. 2025 Jul 20;25(1):1087. doi:10.1186/s12909-025-07707-5. PMID: 40685343; PMCID: PMC12278541.
  16. Shikino K, Nishizaki Y, Fukui S, Kataoka K, Yokokawa D, Shimizu T, Yamamoto Y, Nagasaki K, Kobayashi H, Tokuda Y. Resident Physician Recognition of Tachypnea in Clinical Simulation Videos in Japan: Cross-Sectional Study. JMIR Med Educ. 2025 Jul 31;11:e72640. doi: 10.2196/72640. PMID: 40743513.

（２）和文原著論文?総説

2024年業績

?（１）英文論文

  1. Yamamoto Y, Matsumura M. Cardiac Tamponade Due to Purulent Pericarditis. Am J Med. 2024 Jan;137(1):e6-e7. doi: 10.1016/j.amjmed.2023.07.026. Epub 2023 Sep 9. PMID: 37690504.
  2. Masuda H, Yamamoto Y, Kimura S, Matsuda K, Kobayashi K, Ae R. Spontaneous Abdominal Wall Hematoma: Early Recurrence without an Anticoagulant in an Elderly Woman Receiving Chronic Corticosteroid Treatment. Intern Med. 2024; 63(14): 2097-2100. PMID: 38008449
  3. Kutsuna S, Ohbe H, Kanda N, Matsui H, Yasunaga H. Epidemiological analysis of Legionella pneumonia in Japan: A national inpatient database study. J Epidemiol. 2023 Dec 16. doi: 10.2188/jea.JE20230178. Epub ahead of print. PMID: 38105002.
  4. Nagasaki K, Kobayashi H, Nishizaki Y, Kurihara M, Watari T, Shimizu T, Yamamoto Y, Shikino K, Fukui S, Nishiguchi S, Katayama K, Tokuda Y. Associationof sleep quality with duty hours, mental health, and medical errors amongJapanese postgraduate residents: a cross-sectional study. Sci Rep. 2024 Jan17;14(1):1481. doi: 10.1038/s41598-024-51353-8. PMID: 38233476; PMCID:PMC10794685.
  5. Shikino K, Nishizaki Y, Fukui S, Yokokawa D, Yamamoto Y, Kobayashi H, Shimizu T, Tokuda Y. Development of a Clinical Simulation Video to Evaluate Multiple Domains of Clinical Competence: Cross-Sectional Study. JMIR Med Educ. 2024 Feb 29;10:e54401. doi: 10.2196/54401. PMID: 38421691.
  6. Shikino K, Sekine M, Nishizaki Y, Yamamoto Y, Shimizu T, Fukui S, Nagasaki K, Yokokawa D, Watari T, Kobayashi H, Tokuda Y. Distribution of internal medicine rotations among resident physicians in Japan: a nationwide, multicenter, cross- sectional study. BMC Med Educ. 2024 Mar 20;24(1):316. doi: 10.1186/s12909-024-05314-4. PMID: 38509553.
  7. Sato H, Yamamoto Y, Kaizuka A, Ohtaki Y, Toda M, Fujishima S, Shirahata N, Ae R, Kanno T. Appendicitis after endoscopic band ligation for massive ileocecal hemorrhage. DEN Open. 2024; 5(1): e392. PMID: 38808314
  8. Kataoka K, Nishizaki Y, Shimizu T, Yamamoto Y, Shikino K, Nojima M, Nagasaki K, Fukui S, Nishiguchi S, Katayama K, Kurihara M, Ueda R, Kobayashi H, Tokuda Y. Hospital Use of a Web-Based Clinical Knowledge Support System and In-Training Examination Performance Among Postgraduate Resident Physicians in Japan: Nationwide Observational Study. JMIR Med Educ. 2024; 10: e52207. PMID: 38825848
  9. Shikino K, Shimizu T, Otsuka Y, Tago M, Takahashi H, Watari T, Sasaki Y, Iizuka G, Tamura H, Nakashima K, Kunitomo K, Suzuki M, Aoyama S, Kosaka S, Kawahigashi T, Matsumoto T, Orihara F, Morikawa T, Nishizawa T, Hoshina Y, Yamamoto Y, Matsuo Y, Unoki Y, Kimura H, Tokushima M, Watanuki S, Saito T, Otsuka F, Tokuda Y. Evaluation of ChatGPT-Generated Differential Diagnosis for
    Common Diseases With Atypical Presentation: Descriptive Research. JMIR Med Educ. 2024 Jun 21;10:e58758. doi: 10.2196/58758. PMID: 38915174; PMCID: PMC11199925.
  10. Imai T, Kato N, Kanda N, Hashimoto H, Yamana H, Hatakeyama S. Risk of Urogenital Bacterial Infection with Sodium-Glucose Cotransporter-2 Inhibitors: A Retrospective Cohort Study Using a Claims Database. Diabetes Ther. 2024 Aug;15(8):1821-1830. doi: 10.1007/s13300-024-01613-7. Epub 2024 Jul 3. PMID: 38958909; PMCID: PMC11263449.
  11. Kashiwagi S, Kanda N, Yoshida M, Wakimoto Y, Ohbe H, Nakamura K. Effects of early enteral nutrition on persistent inflammation, immunosuppression, and catabolism syndrome in critically ill patients: A claims database study using a propensity score analysis. Clin Nutr. 2024 Aug;43(8):1872-1879. doi: 10.1016/j.clnu.2024.06.033. Epub 2024 Jun 28. PMID: 38968719.
  12. Fukui S, Shimizu T, Nishizaki Y, Shikino K, Yamamoto Y, Kobayashi H, Tokuda Y.? The Utility of Wearable Cameras in Developing Examination Questions and Answers on Physical Examinations: Preliminary Study. JMIR Med Educ. 2024; 10: e53193. PMID: 39037348
  13. Yoshida M, Kanda N, Kashiwagi S, Wakimoto Y, Ohbe H, Nakamura K. Relationship between very early enteral nutrition and persistent inflammation,
    immunosuppression, and catabolism syndrome in cardiovascular surgery patients: a propensity score-matched study. Am J Clin Nutr. 2024 Jul 20:S0002-9165(24)00613-0. doi: 10.1016/j.ajcnut.2024.07.016. Epub ahead of print. PMID: 39038737.
  14. Inaba T,?Yamamoto Y, Hirayama K, Kobayashi T, Izumi N, Sakamoto H, Hatakeyama S, Matsumura M. Esophageal and Ileal Ulcers Caused by Hydroxycarbamide: A Case Report and Literature Review. Intern Med. 2024 Aug 10. doi: 10.2169/internalmedicine.4105-24.?Online ahead of print. PMID: 39135249.
  15. Kashiwagi S, Kanda N, Nakamura K. Letter to the Editor-“Effects of early enteral nutrition on persistent inflammation, immunosuppression, and catabolism syndrome in critically ill patients”. Clin Nutr. 2024 Nov;43(11):135-136. doi: 10.1016/j.clnu.2024.09.046. Epub 2024 Sep 30. PMID: 39378562.
  16. Nishiguchi S, Nishizaki Y, Hamaguchi M, Goto A, Inamori M, Shikino K, Shinozaki T, Kataoka K, Shimizu T,?Yamamoto Y, Fukui S, Kobayashi H, Tokuda Y. Experience of caring for patients with COVID-19 and educational achievement among Japanese resident physicians: a nationwide survey with general medicine in-training examination. BMC Med Educ. 2024; 24(1): 1125. PMID: 39390486.
  17. Imai T, Hashimoto H, Kanda N, Sasabuchi Y, Matsui H, Yasunaga H, Hatakeyama S. Effect of calcium channel blockers on influenza incidence: a population-based retrospective cohort study using administrative claims data in Japan. BMJ Open. 2024 Oct 15;14(10):e084092. doi: 10.1136/bmjopen-2024-084092. PMID: 39414280; PMCID: PMC11481128.
  18. Shikino K, Nishizaki Y, Kataoka K, Nojima M, Shimizu T,?Yamamoto Y, Fukui S, Nagasaki K, Yokokawa D, Kobayashi H, Tokuda Y. Association between physicians’ maldistribution and core clinical competency of resident physicians: a nationwide cross-sectional study. BMJ Open. 2024; 14(10): e083184. PMID: 39424384.
  19. Hakoda S,